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Clinical trials are carefully controlled studies designed to test the safety and effectiveness of new medical treatments. When researchers have...

GMAT Craft and Structure : (Structure) Questions

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Craft and Structure
Words in Context
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Clinical trials are carefully controlled studies designed to test the safety and effectiveness of new medical treatments. When researchers have a ______ that a particular drug might reduce symptoms of a specific condition, they can design a randomized trial to evaluate that idea by comparing outcomes between patients who receive the treatment and those who receive a placebo.

Which choice completes the text with the most logical and precise word or phrase?

A

hypothesis

B

protocol

C

diagnosis

D

summary

Solution

Step 1: Decode and Map the Passage

Part A: Create Passage Analysis Table

Text from PassageAnalysis
'Clinical trials are carefully controlled studies designed to test the safety and effectiveness of new medical treatments.'
  • What it says: Clinical trials = controlled studies, test safety + effectiveness of new treatments
  • What it does: Defines what clinical trials are
  • What it is: Definition/Context
'When researchers have a _______'
  • What it is: Missing logical connector
'that a particular drug might reduce symptoms of a specific condition,'
  • What it says: Drug might reduce symptoms of condition
  • What it does: Describes what researchers think about the drug
  • What it is: Potential outcome/theory
'they can design a randomized trial to evaluate that idea by comparing outcomes between patients who receive the treatment and those who receive a placebo.'
  • What it says: Researchers design randomized trial to test idea, compare treatment vs placebo groups
  • What it does: Explains how researchers test their thinking
  • What it is: Method/Process

Part B: Provide Passage Architecture & Core Elements

Main Point: Clinical trials are the method researchers use to scientifically test whether their ideas about potential treatments are actually effective.

Argument Flow: The passage establishes what clinical trials are, then explains the process - researchers start with some kind of idea about a treatment's potential, then design controlled studies to test whether that idea holds up in practice.

Step 2: Interpret the Question Precisely

This is a fill-in-the-blank question asking us to choose the best logical connector. The answer must create the right relationship between what comes before and after the blank.

Step 3: Prethink the Answer

  • Looking at our analysis, researchers need to have something that leads them to design a trial
  • The blank comes right before 'that a particular drug might reduce symptoms' - so we need a word that describes what researchers have when they think a treatment might work but haven't proven it yet
  • The word should indicate:
    • An unproven idea or theory
    • Something testable through experimentation
    • The starting point for scientific investigation
  • So the right answer should describe the kind of scientific theory or educated guess that researchers test through clinical trials
Answer Choices Explained
A

hypothesis

✓ Correct
  • 'Hypothesis' perfectly fits - it's an unproven scientific theory that can be tested
  • Matches our prethinking: researchers form hypotheses (testable theories) before designing experiments
  • Creates logical flow: have hypothesis then design trial to test it
B

protocol

✗ Incorrect
  • 'Protocol' refers to the experimental procedure itself
  • Doesn't make sense logically - you don't 'have a protocol that a drug might work'
  • What trap this represents: Students might confuse the research method (protocol) with the initial idea being tested
C

diagnosis

✗ Incorrect
  • 'Diagnosis' means identifying what disease someone has
  • Completely wrong context - researchers aren't diagnosing patients here, they're testing treatments
  • Doesn't fit grammatically with 'that a drug might reduce symptoms'
D

summary

✗ Incorrect
  • 'Summary' is a recap of existing information
  • Wrong logical relationship - researchers don't 'have a summary that a drug might work'
  • Doesn't capture the forward-looking, testable nature of what researchers need
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