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The following text is adapted from a research methodology handbook. Dr. Martinez, a biochemist, spent months in her laboratory attempting...

GMAT Craft and Structure : (Structure) Questions

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Craft and Structure
Words in Context
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The following text is adapted from a research methodology handbook. Dr. Martinez, a biochemist, spent months in her laboratory attempting to synthesize a novel compound that could potentially treat autoimmune disorders. Through careful manipulation of molecular structures and precise control of reaction conditions, she successfully produced the desired therapeutic molecule.

As used in the text, what does the word "synthesize" most nearly mean?

A

Create

B

Analyze

C

Isolate

D

Observe

Solution

Step 1: Decode and Map the Passage

Part A: Create Passage Analysis Table

Text from PassageAnalysis
"Dr. Martinez, a biochemist, spent months in her laboratory attempting to synthesize a novel compound that could potentially treat autoimmune disorders."
  • What it says: Dr. M (biochemist) → months in lab trying to synthesize new compound for autoimmune treatment
  • What it does: Introduces the scientist and her research goal
  • What it is: Context/setup
"synthesize"
  • What it is: Target word - meaning to be determined from context
"Through careful manipulation of molecular structures and precise control of reaction conditions, she successfully produced the desired therapeutic molecule."
  • What it says: Careful molecular work + controlled conditions → successfully produced the molecule
  • What it does: Explains her method and confirms success
  • What it is: Evidence of achievement

Part B: Provide Passage Architecture & Core Elements

Main Point: Dr. Martinez successfully created a new therapeutic compound through careful laboratory work.

Argument Flow: The passage establishes Dr. Martinez's research objective to synthesize a new compound, then shows how her methodical approach led to successfully producing the desired therapeutic molecule.

Step 2: Interpret the Question Precisely

This is a fill-in-the-blank question asking us to choose the best logical connector. The answer must create the right relationship between what comes before and after the blank.

Step 3: Prethink the Answer

  • Looking at the context, Dr. Martinez is "attempting to synthesize a novel compound" and the passage tells us she "successfully produced the desired therapeutic molecule."
  • The word "synthesize" is directly connected to producing or making something new.
  • She's working in a lab, manipulating molecular structures to bring something into existence that didn't exist before.
  • The right answer should capture the idea of making, creating, or producing something new through deliberate scientific processes.
Answer Choices Explained
A

Create

✓ Correct

  • "Create" perfectly captures what Dr. Martinez is doing - making a new compound that didn't exist before.
  • This matches the context where she's working to bring a novel therapeutic molecule into existence.
  • The passage confirms success by saying she "produced" the molecule, which aligns with creating.
B

Analyze

✗ Incorrect

  • "Analyze" means to examine or study something that already exists.
  • Dr. Martinez isn't studying an existing compound - she's making a new one.
C

Isolate

✗ Incorrect

  • "Isolate" means to separate something from other substances.
  • The passage indicates she's creating something novel, not separating existing components.
D

Observe

✗ Incorrect

  • "Observe" means to watch or notice something.
  • Dr. Martinez is actively creating through "manipulation of molecular structures," not passively watching.
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