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Examining tissue samples under high magnification, Dr. Martinez's research team observed cellular structures that resembled the characteristic markers...

GMAT Expression of Ideas : (Expression) Questions

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Expression of Ideas
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Examining tissue samples under high magnification, Dr. Martinez's research team observed cellular structures that resembled the characteristic markers of autoimmune inflammation. _____ advanced genetic sequencing revealed that the inflammation was actually caused by a rare hereditary enzyme deficiency, completely changing the treatment approach for affected patients.

Which choice completes the text with the most logical transition?

A

Eventually,

B

Similarly,

C

Therefore,

D

Meanwhile,

Solution

Step 1: Decode and Map the Passage

Part A: Create Passage Analysis Table

Text from PassageAnalysis
"Examining tissue samples under high magnification, Dr. Martinez's research team observed cellular structures that resembled the characteristic markers of autoimmune inflammation."
  • What it says: Team looked at tissue and saw structures that looked like autoimmune markers
  • What it does: Introduces initial research findings based on visual observation
  • What it is: Context/Initial finding
[MISSING TRANSITION]
  • What it is: Missing logical connector
"advanced genetic sequencing revealed that the inflammation was actually caused by a rare hereditary enzyme deficiency, completely changing the treatment approach for affected patients."
  • What it says: Gene testing showed real cause was enzyme problem, not autoimmune, leading to treatment change
  • What it does: Provides contrasting discovery that corrects the initial interpretation
  • What it is: Corrective evidence/New finding

Part B: Provide Passage Architecture & Core Elements

Main Point: Advanced genetic testing revealed that what initially appeared to be autoimmune inflammation was actually caused by a hereditary enzyme deficiency, leading to a completely different treatment approach.

Argument Flow: The passage moves from an initial visual observation that suggested one diagnosis to more sophisticated testing that revealed the true cause and necessitated a different treatment strategy. The missing transition needs to bridge the gap between these two sequential research phases.

Step 2: Interpret the Question Precisely

This is a fill-in-the-blank question asking us to choose the best logical connector. The answer must create the right relationship between what comes before and after the blank.

Step 3: Prethink the Answer

  • From our analysis, we see that the research team first made observations based on visual examination, and then later used advanced genetic sequencing that revealed different information
  • The relationship here is temporal—one research method was used first, then another method was employed that provided more definitive results
  • The right transition should indicate that the genetic sequencing happened after the initial tissue examination, showing a progression in the research process
Answer Choices Explained
A

Eventually,

✓ Correct

  • "Eventually" indicates that the genetic sequencing happened after some time following the initial observations
  • Creates the logical flow: first they observed, then later advanced testing revealed the truth
  • Matches our prethinking about temporal sequence in the research process
B

Similarly,

✗ Incorrect

  • "Similarly" suggests the genetic sequencing findings would be comparable to the initial observations
  • Actually contradicts the passage since the genetic testing revealed something completely different from what was initially observed
C

Therefore,

✗ Incorrect

  • "Therefore" implies the genetic sequencing results were a logical consequence of the initial observations
  • Does not fit because the sequencing revealed that the initial interpretation was wrong, not a conclusion drawn from it
D

Meanwhile,

✗ Incorrect

  • "Meanwhile" suggests the genetic sequencing was happening at the same time as the tissue examination
  • Does not capture the sequential nature of the research process described
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